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Milk EPD – Does it Work?

Dr. Wade Shafer, Ph.D wrote this article back in 2011 and when we discussed the Milk EPD again last summer, he forwarded this to me and stated the logic still applies today. If you have questions on the Milk EPD, this does a great job breaking it down for us.
An Examination of Milk EPDs
A discussion of the validity of EPDs for milk.
By Wade Shafer, Ph.D., ASA Director of Performance Programs
Published in March 2011
Over the last several years I have fielded too many calls to count from breeders feeling that Milk EPDs do not do justice in gauging their herd’s genetic milking ability. Though you may not be one of the many breeders who have voiced reservations about Milk EPDs to me directly, I suspect
you may have had qualms with them from time to time. In talking with people of other breeds, this sentiment is not unique to Simmental breeders. Though many breeders may question the validity of milk EPDs, they are without a doubt the best predictor we have
of animals’ genetic level for milk. That said, when we scrutinize the situation, breeders’ skepticism about Milk EPDs is understandable. In the following paragraphs I will explain why EPDs gauge genetic level for
milk as accurately as possible and offer up my opinions as to why breeders often question their validity. To understand a widely held belief, it usually helps to get at the root of it. What is at the core of breeders’ misgivings about Milk EPDs? From my experience, breeders seldom question milk EPDs on sires — rather, doubt tends to permeate when cows in their herd wean big calves yet have lower-percentile
Milk EPDs. On the surface, their skepticism seems justified. It just seems logical that high-producing cows should have upper-end milk EPDs. It turns out there are solid reasons why a top producing cow does not
necessarily possess genes for high levels of milk production — and, therefore, should not have high-level milk EPDs. To gain some perspective, let’s take a look at factors affecting the measurement
we use to gauge milking ability — weaning weights. (Obviously, we do not have the latitude to measure milk directly, as does the dairy industry. Even if we could, the trait we are concerned with in the beef business is the pounds of weaned calf expected from a cow due to the genes she
possesses for milk and mothering ability — which we can compute using weaning weights.) From a cow’s genetic perspective, the weaning weight of her calf is affected by her own milk genes and half of her weaning weight genes (the calf carries half of her genes). (This fact is the reason
Maternal Weaning Weight EPD is calculated as Milk EPD+ ½ Weaning Weight EPD.) Beyond that, there are non-genetic factors affecting the calf’s weaning weight (age of its dam, stocking rate, weather, creep feed, and many other non genetic effects we are not able to distinguish).
Due to the myriad of factors affecting weaning weight, using actual and/or adjusted weaning weights and/or ratios will not serve us well in predicting an animal’s genetic value for milk production. One glaring shortcoming of these statistics is that they do not partition weaning weight into separate growth and milk components — an obvious requisite for assessing milk genetics. Besides that monumental failing, weights and ratios do little to nothing when it comes to sifting through the non-genetic influences on weaning weight and they ignore information on relatives. Because the methodology used to calculate EPDs (Best Linear Unbiased Prediction; BLUP) allows us to parse weaning weight by the factors that impact it, EPDs permit us to zero in on an animal’s genetics for milk — independent of all the other factors. This is accomplished by leveraging the sophisticated statistical techniques of BLUP on the 6 million+ weaning weights in our database. These features make EPDs vastly superior to other methods of gauging milk genetics.
After extolling the virtues of EPDs, how is it that we can have cows that wean heavy calves with poor milk EPDs (and vice versa)? One obvious reason is that these cows may be weaning heavy calves via exceptional
growth genes they pass to their calves. (Just look through ASA’s database and you will find plenty of animals that have low Milk EPDs but high Maternal Weaning Weight EPDs due to their extreme growth. Remember, Maternal Weaning Weight EPD = Milk EPD+ ½ Weaning Weight.) A typical retort to this assertion is “how could the calf express exceptional growth if the cow did not give loads of milk?” Though high levels of milk certainly help a calf express its growth potential, a calf gets a significant amount of its nutrients from sources other than milk
(particularly after the first few months). Another plausible cause for a heavy weaning calf out of a low milk EPD cow is simply that she produced lots of milk. In these circumstances, our genetic evaluation is telling us that the reason for the souped-up milk production is likely non-
genetic in nature. This is a big pill to swallow, as we tend to assume
that a heavy milking cow must be genetically outstanding for milk
production; however, since milk production is only low to moderately
heritable we should not be surprised to have heavy milking cows that
are below average genetically, and vice versa. From a genetic evaluation standpoint, milk’s meager heritability means that it takes more data to move Milk EPDs and improve accuracies than it does with more heritable traits (e.g., growth and carcass). Since a cow is quite limited in the number of calves she can have naturally, unless she has numerous daughters (typically only possible for donor cows) and they have many calves or her sire or maternal grandsire change dramatically for milk, a colossal shift in her milk EPD from where she starts is not in the cards. A big jump in accuracy is just as unlikely. These limitations do not in any way imply fault with EPDs, the limitations are simply a function of biology — low heritability and small numbers of offspring are not conducive to accurate estimation. Always keep in mind, however, even though a cow’s Milk EPDs may not be highly accurate, research has clearly shown that they are far and away the most accurate estimate of her genetic merit for milk. In our population we have estimated the heritability of milk to be 16%. This means 84% (100% – 16%) of the differences in milk production between cows during a lactation are due to non-genetic factors — and that is after we remove differences due to age and contemporary group (i.e., herd, pasture). Given these circumstances, it iseasy to see that a cow’s milk production ability may be very different than the genes she possesses for the trait. -
AI Sire and Donor Dam Requirements

We will outline the AI sire and Donor Dam requirements for specific Association’s below.
Disclaimer: board policy is subject to change. It is ALWAYS best to confirm the breed’s current DNA testing policy before collecting a sire or flushing a female.American Angus Association (AAA)
AI Sires and Donor Dams are required to have DNA parentage markers on file with Angus Genetics Inc. (AGI).
AI Sires born after January 1, 2018 are required to have testing for all genetic conditions that are commercially monitored by AAA.
Starting on page 46 of the Breeders Reference Guide it addresses AI requirements. Page 35 goes over embryo calf registrations, including donor dam requirements.Helpful tip:
The most efficient and cost effective way to test for the genetic conditions is to add them to your AngusGS or HD50K genomic testing request when submitting your DNA testing to AGI. Total cost is presently $55.00 ($37.00 for the genomic testing and $18.00 for all genetic conditions) and then the sire is approved for AI use and collection.American Simmental Association (ASA)
AI Sires and Donor Dams are required to have a GGP100K genomic test or other breed Association equivalent (if registered with another breed as the animal’s primary) in order to be approved with the ASA for AI and donor use. ASA website link to DNA requirements
In addition, if an AI sire or Donor Dam displays a risk or carrier in lineage for genetic conditions that ASA monitors (AM, NH, CA, DD, TH, PHA or OS) they will need to be tested in order to prevent genetic holds from taking place on AI sired or ET progeny.
*Note: if the AI sire or Donor Dam displays a risk or carrier in lineage for genetic conditions but is unavailable for testing, the owner of the progeny can elect to test the progeny for genetic conditions and upon doing so the progeny will be removed from genetic hold and receive EPDs.If your AI sire or Donor Dam is registered with another breed Association as their primary breed and you are importing them into the ASA database as a Foreign registration, here is what you will need the primary breed Association to forward along to ASA once the animal has been registered with ASA.
– A copy of the SNP parentage markers
– Confirmation of genomic testing panel for the animal, i.e., AngusGS, HD50K, GGP100K, 150K, 80K, etc.
– Date the animal was genomic tested
All of the above information can be forwarded from the primary breed to dna@simmgene.com
As long as ASA requirements have been met, the foreign animal will be updated as an approved AI sire/Donor Dam with ASA.Red Angus American Association (RAAA)
AI Sires and Donor Dams are required to have Single Nucleotide Polymorphism (SNP) DNA parentage markers on file with RAAA.
ALL sires, including pasture sires, beginning with calves born after January 1, 2017 are required to have SNP DNA parentage markers on file with RAAA.
DNA Testing Requirements begin on page 40Genetic Defect Testing Policy applies to AI sires and Donor Dams if they display a carrier in the lineage for one of the RAAA monitored conditions. Page 37 and 38 go over this policy in the above DNA testing requirements link.
American Hereford Association (AHA)
AI Sires are required to have a DNA profile and be confirmed (qualified) back to both parents to have an AI permit issued.
Donor dams must have a DNA profile on file with ASA to have ET calves reported.
All sires, including herd sires, born after January 1, 2011 are required to be DNA genotyped at the official AHA laboratory prior to progeny being eligible for registration.DNA requirements start on page 26
American Gelbvieh Association (AGA)
AI sires are required as of March 1, 2013 to have genomics testing with parentage markers minimum of GGP-HD, tested for all monitored genetic conditions and be parent verified. In addition, they will need an AI Permit which is a one time $50.00 fee and are eligible for their permit to be issued once the required DNA testing has been completed.
Effective January 1, 2016 all sires are required to have a minimum of a genomic GGP-LD test on file with AGA. This includes imported sires from other breed associations.Donor dams as of March 1, 2013 to have genomics testing with parentage markers minimum of GGP-HD, tested for all monitored genetic conditions and be parent verified. This includes imported donor dams from other breed associations.
DNA requirements start on page 9
American International Charolais Association (AICA)
AI sires used out-of-herd must be DNA tested before the progeny can be registered.
*There is only one current genetic condition being monitored in the AICA population and it is Progressive Ataxia(PA), however, there are no testing requirements at this time but it is encouraged to test sires for PA if their status is unknown.Donor dams must be DNA tested.
AICA DNA requirements are on page 5 and page 10 for AI
More breeds will be added soon – let me know which breeds would like to see listed here.
North American Limousin Foundation (NALF)
AI sires born on or after January 1, 2015 will be required to have a high density (50K or greater) SNP profile on file in addition to parent verification.
Donor dams born on or after January 1, 2015 will be required to have a high density (50K or greater) SNP profile on file in addition to sire verification.
ET calves born on or after January 1, 2014 must be parent verified to both sire and dam through SNP typing.
Genetic Conditions
Any animal with a documented carrier of AM, CA, NH, OS, TH, PHA, or protophyria in the pedigree, unless the intermediary ancestors are tested-free or designated pedigree-free.
Any sire or embryo donor dam with 1/8 blood or more of the defective gene source (breed, line, herd) unless the intermediary ancestors are tested-free or pedigree-free.NALF DNA requirements begin on page 4
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Year Letters and Locations

Year Letters
If you utilize the year letters in your tagging systems (or have to for registration purposes), here is an easy reference guide for you. Keep in mind, the letters in the alphabet we skipp are: I, O, Q and V.

Location of Tattoo or Brand

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Common Parentage Terminology

All information contained on this page is penned by Data Genie LLC and permission to reprint or publish any/all content needs to be granted by the owner. Thank you.
I receive questions weekly about parentage results and how to interpret them. Having a basic understanding of key terminology used by Associations is helpful. Keep in mind, breeders submit DNA parentage testing to confirm likely sire/dam for the offspring. Submitting potential candidate parent(s) for an offspring is crucial to locating the appropriate sire and dam. Depending on genetic variation within a breed or in herd population, you can have multiple parent(s) qualify to an offspring due to the close relationship and number of markers being utilized in comparisons. If you have a closely related population it is always encouraged to have SNP parentage markers for the possible sire and dam’s of the offspring so that a trio comparison can be performed and exclude the incorrect mating(s) for the offspring. If you have questions on parentage, reach out or comment below.
Qualified – offspring does not exclude to parent(s) provided
Exclusion – offspring does not qualify to parent(s) provided
*Mating Exclusion – offspring qualifies to sire and dam independently, but does not qualify as a mated pair
Trio Qualification – offspring qualifies to sire, dam and as a mated pair
Not on File – parentage markers not located in Association database for the given animal
Re-Check – Compare offspring to alternate parent(s)
Marker Exclusions – how many markers are not matching from parent to offspring
– This is great information to be aware of so alternate parent(s) can be potentially narrowed down
Common Markers – how many markers were compared between parent and offspring
Sire Verified – sire listed on pedigree has qualified as the likely sire for the animal, dam does not have DNA parentage on file for comparison
Dam Verified – dam listed on pedigree has qualified as the likely dam for the animal, sire does not have DNA parentage on file for comparison
Parent Verified – parents listed on pedigree have qualified as the likely parents for the animal*Mating Exclusions
Mating exclusions are tough to explain, can be complicated and frustrating for all involved. Here’s my best attempt at explaining how this happens.
Offspring is compared to sire, dam and then as a mated pair. There are instances where the calf qualifies to the sire and dam independently but not to the mating. For example, if the offspring is A/T and the sire is T/T, qualifies. Dam is T/T, qualifies but when put together we have a calf that received an A from a parent and neither parent in this case had an A to give. Therefore that counts as a “Mating exclusion”. Offspring are typically allowed 1 marker exclusion per 100 markers compared to be considered a qualifying result. Oftentimes mating exclusions can be cleared up in the following ways:
– likely parent may be closely related to nominated parent, i.e., full siblings or parent/offspring scenario
– asking for evaluation of SNP marker calls to ensure calls are solid at exclusion markers for sire, dam and offspring
– submitting a new sample for testing using a different sample type and test, i.e., if you ran a genomic panel the first time via TSU, submitting a blood/hair card for SeekSire (parentage only) testing the 2nd time
If you’re not a Data Genie client, consulting directly with the breed association DNA staff is always advised to get a better feel for your specific case.












